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1

Zinc transporter 8 autoantibodies in fulminant, acute-onset, and slow-onset patients with type 1 diabetes

Eiji Kawasaki, Kan Nakamura, Genpei Kuriya, Tsuyoshi Satoh, Masakazu Kobayashi, Hironaga Kuwahara, Norio Abiru, Hironori Yamasaki, Nobuo Matsuura, Junnosuke Miura, Yasuko Uchigata, Katsumi Eguchi

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2011

Language:

english

File:

PDF, 174 KB

english, 2011

2

Current knowledge of Japanese type 1 diabetic syndrome

Norio Abiru, Eiji Kawasaki, Katsumi Eguch

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2002

Language:

english

File:

PDF, 169 KB

english, 2002

3

Increased incidence of pre-diabetes mellitus at a department of rheumatology: a retrospective study

Tomoki Origuchi, Satomi Yamaguchi, Akiyo Inoue, Yoshie Kazaura, Naomi Matsuo, Norio Abiru, Atsushi Kawakami, Katsumi Eguchi

Journal:

Modern Rheumatology

Year:

2011

Language:

english

File:

PDF, 1.62 MB

english, 2011

4

Maternal dietary n-6/n-3 fatty acid ratio affects type 1 diabetes development in the offspring of non-obese diabetic mice

Yukiko Kagohashi, Norio Abiru, Masakazu Kobayashi, Michio Hashimoto, Osamu Shido, Hiroki Otani

Journal:

Congenital Anomalies

Year:

2010

Language:

english

File:

PDF, 585 KB

english, 2010

5

Induction of Insulin Autoantibodies and Protection from Diabetes with Subcutaneous Insulin B: 9-23 Peptide without Adjuvant

EDWIN LIU, NORIO ABIRU, HIROAKI MORIYAMA, DONGMEI MIAO, GEORGE S. EISENBARTH

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 1.32 MB

english, 2002

6

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

Nakayama, Maki, Abiru, Norio, Moriyama, Hiroaki, Babaya, Naru, Liu, Edwin, Miao, Dongmei, Yu, Liping, Wegmann, Dale R., Hutton, John C., Elliott, John F.

Journal:

Year:

2005

Language:

english

File:

PDF, 330 KB

english, 2005

7

Distinct IA-2 Autoantibody Epitope Recognition between Childhood-Onset and Adult-Onset Type 1 Diabetes

EIJI KAWASAKI, YASUNORI SERA, NORIO ABIRU, MIKAKO YAMAUCHI, MASAKO OZAKI, KENICHI YAMAKAWA, TAKAHIRO ABE, SHIGEO UOTANI, HIRONORI YAMASAKI, YOSHIHIKO YAMAGUCHI, KATSUMI EGUCHI

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 1.21 MB

english, 2002

8

In Vivo Expression of B:9-23 Peptide/I-Ag7 Complex May Abrogate the Inhibition of Diabetes Induced by RGD-Fiber-Mutant Adenovirus in NOD Mice

NORIO ABIRU, FUYAN SUN, EIJI KAWASAKI, HIRONORI YAMASAKI, KATSUYA OSHIMA, YUJI NAGAYAMA, HIROYUKI MIZUGUCHI, TAKAO HAYAKAWA, DONGMEI MIAO, EDWIN LIU, GEORGE S. EISENBARTH, KATSUMI EGUCHI

Journal:

Annals of the New York Academy of Sciences

Year:

2003

Language:

english

File:

PDF, 232 KB

english, 2003

9

Interleukin-10 Gene Promoter Region Polymorphisms in Patients with Type 1 Diabetes and Autoimmune Thyroid Disease

AKANE IDE, EIJI KAWASAKI, NORIO ABIRU, FUYAN SUN, TETSUYA FUKUSHIMA, REIKO ISHII, RYOKO TAKAHASHI, HIRONAGA KUWAHARA, NARUHIRO FUJITA, ATSUSHI KITA, MISA IMAIZUMI, KATSUYA OSHIMA, TOSHIRO USA, SHIGEO

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 103 KB

2003

10

Establishing Insulin 1 and Insulin 2 Knockout Congenic Strains on NOD Genetic Background

JOHANNA PARONEN, HIROAKI MORIYAMA, NORIO ABIRU, KAMILA SIKORA, EVIE MELANITOU, SUNANDA BABU, FEI BAO, EDWIN LIU, DONGMEI MIAO, GEORGE S. EISENBARTH

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 906 KB

2003

11

Epitope Analysis of GAD65 Autoantibodies in Japanese Patients with Autoimmune Diabetes

EIJI KAWASAKI, NORIO ABIRU, AKANE IDE, FUYAN SUN, TETSUYA FUKUSHIMA, RYOKO TAKAHASHI, HIRONAGA KUWAHARA, NARUHIRO FUJITA, ATSUSHI KITA, KATSUYA OSHIMA, SHIGEO UOTANI, HIRONORI YAMASAKI, YOSHIHIKO YAMA

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 7.29 MB

2003

12

Association of Interleukin-18 Gene Promoter Polymorphisms in Type 1 Diabetes and Autoimmune Thyroid Disease

AKANE IDE, EIJI KAWASAKI, NORIO ABIRU, FUYAN SUN, TETSUYA FUKUSHIMA, REIKO ISHII, RYOKO TAKAHASHI, HIRONAGA KUWAHARA, NARUHIRO FUJITA, ATSUSHI KITA, MISA IMAIZUMI, KATSUYA OSHIMA, TOSHIRO USA, SHIGEO

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 119 KB

2003

13

Establishment of Native Insulin-Negative NOD Mice and the Methodology to Distinguish Specific Insulin Knockout Genotypes and a B:16 Alanine Preproinsulin Transgene

MAKI NAKAYAMA, HIROAKI MORIYAMA, NORIO ABIRU, SUNANDA R. BABU, KAMILA SIKORA, MARCELLA LI, DONGMEI MIAO, JOHN C. HUTTON, JOHN F. ELLIOTT, GEORGE S. EISENBARTH

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 848 KB

english, 2004

14

Stromal Cell-Derived Factor-1 Chemokine Gene Variant in Patients with Type 1 Diabetes and Autoimmune Thyroid Disease

EIJI KAWASAKI, AKANE IDE, NORIO ABIRU, MASAKAZU KOBAYASHI, TETSUYA FUKUSHIMA, HIRONAGA KUWAHARA, ATSUSHI KITA, SHIGEO UOTANI, HIRONORI YAMASAKI, KATSUMI EGUCHI

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 93 KB

english, 2004

15

Humoral Immune Response to Islet Autoantigens in Japanese Patients with Type 1 Diabetes

Eiji Kawasaki, Genpei Kuriya, Tsuyoshi Satoh, Keiichiro Fujishima, Akie Moriuchi, Keiko Fukushima, Masako Ozaki, Norio Abiru, Hironori Yamasaki, Katsumi Eguchi

Journal:

Annals of the New York Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 134 KB

english, 2008

16

Multiple genes/multiple autoantigens role in type 1 diabetes

Norio Abiru, George S. Eisenbarth

Journal:

Clinical Reviews in Allergy & Immunology

Year:

2000

Language:

english

File:

PDF, 148 KB

english, 2000

17

Su.11. Poly I:C and Insulin B:9–23 Self-Peptide Accelerate Insulitis Containing Pathogenic and Cd4+Foxp3+ Regulatory Cells Which Can Inhibit the Development of Diabetes

Keiko Fukushima, Norio Abiru, Masakazu Kobayashi, Eiji Kawasaki, Hironori Yamasaki, Edwin Liu, George Eisenbarth, Katsumi Eguchi

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 41 KB

english, 2006

18

Differences in the humoral autoreactivity to zinc transporter 8 between childhood- and adult-onset type 1 diabetes in Japanese patients

Eiji Kawasaki, Kan Nakamura, Genpei Kuriya, Tsuyoshi Satoh, Masakazu Kobayashi, Hironaga Kuwahara, Norio Abiru, Hironori Yamasaki, Nobuo Matsuura, Junnosuke Miura, Yasuko Uchigata, Katsumi Eguchi

Journal:

Clinical Immunology

Year:

2011

Language:

english

File:

PDF, 373 KB

english, 2011

19

Autoantibodies to Glutamic Acid Decarboxylase in Patients with Autoimmune Thyroid Disease: Relation to Competitive Insulin Autoantibodies

Eiji Kawasaki, Norio Abiru, Mayumi Yano, Shigeo Uotani, Kazunari Matsumoto, Hiroshi Matsuo, Hironori Yamasaki, Hidefumi Yamamoto, Yoshihiko Yamaguchi, Shoichi Akazawa, Shigenobu Nagataki

Journal:

Journal of Autoimmunity

Year:

1995

Language:

english

File:

PDF, 111 KB

english, 1995

20

Clinical Evaluation of Non-Insulin-Dependent Diabetes Mellitus Patients with Autoantibodies to Glutamic Acid Decarboxylase

Norio Abiru, Hirofumi Takino, Mayumi Yano, Eiji Kawasaki, Hironori Yamasaki, Yoshihiko Yamaguchi, Shoichi Akazawa, Shigenobu Nagataki

Journal:

Journal of Autoimmunity

Year:

1996

Language:

english

File:

PDF, 130 KB

english, 1996

21

Autoantibodies to Multiple Islet Autoantigens in Patients with Abrupt Onset Type 1 Diabetes and Diabetes Diagnosed with Urinary Glucose Screening

Yasunori Sera, Eiji Kawasaki, Norio Abiru, Masako Ozaki, Takahiro Abe, Hirofumi Takino, Hideaki Kondo, Hironori Yamasaki, Yoshihiko Yamaguchi, Shoichi Akazawa, Shigenobu Nagataki, Yasuko Uchigata, Nob

Journal:

Journal of Autoimmunity

Year:

1999

Language:

english

File:

PDF, 216 KB

english, 1999

22

Dual Overlapping Peptides Recognized by Insulin Peptide B:9–23 T Cell Receptor AV13S3 T Cell Clones of the NOD Mouse

Norio Abiru, Dale Wegmann, Eiji Kawasaki, Peter Gottlieb, Eric Simone, George S Eisenbarth

Journal:

Journal of Autoimmunity

Year:

2000

Language:

english

File:

PDF, 127 KB

english, 2000

23

Transient Insulin Autoantibody Expression Independent of Development of Diabetes: Comparison of NOD and NOR Strains

Norio Abiru, Liping Yu, Dongmei Miao, Aristides K Maniatis, Edwin Liu, Hiroaki Moriyama, George S Eisenbarth

Journal:

Journal of Autoimmunity

Year:

2001

Language:

english

File:

PDF, 502 KB

english, 2001

24

Identification of the promoter region required for human adiponectin gene transcription: Association with CCAAT/enhancer binding protein-β and tumor necrosis factor-α

Atsushi Kita, Hironori Yamasaki, Hironaga Kuwahara, Akie Moriuchi, Keiko Fukushima, Masakazu Kobayashi, Tetsuya Fukushima, Ryoko Takahashi, Norio Abiru, Shigeo Uotani, Eiji Kawasaki, Katsumi Eguchi

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 239 KB

english, 2005

25

Combined insulin B:9-23 self-peptide and polyinosinic–polycytidylic acid accelerate insulitis but inhibit development of diabetes by increasing the proportion of CD4+Foxp3+ regulatory T cells in the islets in non-obese diabetic mice

Keiko Fukushima, Norio Abiru, Yuji Nagayama, Masakazu Kobayashi, Tsuyoshi Satoh, Mami Nakahara, Eiji Kawasaki, Hironori Yamasaki, Satoshi Ueha, Koji Matsushima, Edwin Liu, Katsumi Eguchi

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 1.27 MB

english, 2008

26

Prevention of type 1 diabetes: from the view point of β cell damage

Eiji Kawasaki, Norio Abiru, Katsumi Eguchi

Journal:

Diabetes Research and Clinical Practice

Year:

2004

Language:

english

File:

PDF, 115 KB

english, 2004

27

Association between IL-18 gene promoter polymorphisms and CTLA-4 gene 49A/G polymorphism in Japanese patients with type 1 diabetes

Akane Ide, Eiji Kawasaki, Norio Abiru, Fuyan Sun, Masakazu Kobayashi, Tetsuya Fukushima, Ryoko Takahashi, Hironaga Kuwahara, Atsushi Kita, Katsuya Oshima, Shigeo Uotani, Hironori Yamasaki, Yoshihiko Y

Journal:

Journal of Autoimmunity

Year:

2004

Language:

english

File:

PDF, 167 KB

english, 2004

28

CD4+CD25+ naturally occurring regulatory T cells and not lymphopenia play a role in the pathogenesis of iodide-induced autoimmune thyroiditis in NOD-H2h4 mice

Yuji Nagayama, Ichiro Horie, Ohki Saitoh, Mami Nakahara, Norio Abiru

Journal:

Journal of Autoimmunity

Year:

2007

Language:

english

File:

PDF, 912 KB

english, 2007

29

Genetic association between interleukin-10 gene promoter region polymorphisms and type 1 diabetes age-at-onset

Akane Ide, Eiji Kawasaki, Norio Abiru, Fuyan Sun, Ryoko Takahashi, Hironaga Kuwahara, Naruhiro Fujita, Atsushi Kita, Katsuya Oshima, Hiroyuki Sakamaki, Shigeo Uotani, Hironori Yamasaki, Yoshihiko Yama

Journal:

Human Immunology

Year:

2002

Language:

english

File:

PDF, 88 KB

english, 2002

30

Stromal-cell derived factor-1 chemokine gene variant is associated with type 1 diabetes age at onset in Japanese population

Akane Ide, Eiji Kawasaki, Norio Abiru, Fuyan Sun, Tetsuya Fukushima, Ryoko Takahashi, Hironaga Kuwahara, Naruhiro Fujita, Atsushi Kita, Katsuya Oshima, Shigeo Uotani, Hironori Yamasaki, Yoshihiko Yama

Journal:

Human Immunology

Year:

2003

Language:

english

File:

PDF, 97 KB

english, 2003

31

Nondepleting anti-CD4 monoclonal antibody prevents diabetes and blocks induction of insulin autoantibodies following insulin peptide B:9-23 immunization in the NOD mouse

Edwin Liu, Hiroaki Moriyama, Johanna Paronen, Norio Abiru, Dongmei Miao, Liping Yu, Robert M. Taylor, George S. Eisenbarth

Journal:

Journal of Autoimmunity

Year:

2003

Language:

english

File:

PDF, 163 KB

english, 2003

32

Insulin response after treatment depends on fasting plasma glucose level in NIDDM

Kazunari Matsumoto, Shoichi Akazawa, Norio Abiru, Mayumi Yano, Miwa Ishibasi, Shigeo Uotani, Hiroshi Matsuo, Eiji Kawasaki, Hironori Yamasaki, Hidefumi Yamamoto, Yoshihiko Yamaguchi, Shigenobu Nagatak

Journal:

Diabetes Research and Clinical Practice

Year:

1994

Language:

english

File:

PDF, 653 KB

english, 1994

33

Autoantibodies to glutamic acid decarboxylase (GAD), 64000-Mr islet cell protein (64K) antibodies and islet cell antibodies (ICA) in insulin-dependent diabetes mellitus with and without autoimmune diseases in Japan

Shoichi Akawaza, Eiji Kawasaki, Mayumi Yano, Norio Abiru, Yoshihiko Yamaguchi, Shigenobu Nagataki

Journal:

Diabetes Research and Clinical Practice

Year:

1994

Language:

english

File:

PDF, 493 KB

english, 1994

34

Preventing peptide-induced anaphylaxis: Addition of C-terminal amino acids to produce a neutral isoelectric point☆

Liu, Edwin, Moriyama, Hiroaki, Abiru, Norio, Paronen, Johanna, Devendra, Devasenan, Finkelman, Fred D., Eisenbarth, George S.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2004

Language:

english

File:

PDF, 413 KB

english, 2004

35

The effect of regulatory T-cell depletion on the spectrum of organ-specific autoimmune diseases in nonobese diabetic mice at different ages

Nakahara, Mami, Nagayama, Yuji, Ichikawa, Tatsuki, Yu, Liping, Eisenbarth, George S., Abiru, Norio

Journal:

Year:

2011

Language:

english

File:

PDF, 331 KB

english, 2011

36

Novel enzyme-linked immunosorbent assay for bivalent ZnT8 autoantibodies

Kawasaki, Eiji, Tanaka, Megumi, Miwa, Masaki, Abiru, Norio, Kawakami, Atsushi

Journal:

Acta Diabetologica

Year:

2014

Language:

english

File:

PDF, 281 KB

english, 2014

37

Commentary: Modification of the Environment Is Not the Most Efficient Way to Prevent Type 1 Diabetes

Abiru, Norio, Yu, Liping, Redondo, Maria J., Eisenbarth, George S.

Journal:

Diabetes Technology & Therapeutics

Year:

2000

Language:

english

File:

PDF, 569 KB

english, 2000

38

Increased incidence of pre-diabetes mellitus at a department of rheumatology: a retrospective study

Origuchi, Tomoki, Yamaguchi, Satomi, Inoue, Akiyo, Kazaura, Yoshie, Matsuo, Naomi, Abiru, Norio, Kawakami, Atsushi, Eguchi, Katsumi

Journal:

Modern Rheumatology

Year:

2011

Language:

english

File:

PDF, 1.64 MB

english, 2011

39

Association of the GCKR rs780094 polymorphism with metabolic traits including carotid intima-media thickness in Japanese community-dwelling men, but not in women

Murata-Mori, Fumi, Hayashida, Naomi, Ando, Takao, Ikeoka, Toshiyuki, Nakazato, Mio, Sekita, Harutaka, Abiru, Norio, Yamasaki, Hironori, Maeda, Takahiro, Kawakami, Atsushi, Takamura, Noboru

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2014

Language:

english

File:

PDF, 151 KB

english, 2014

40

Multimers and adiponectin gene 276G>T polymorphism in the Japanese population residing in rural areas

Ishibashi, Kiyomi, Takamura, Noboru, Aoyagi, Kiyoshi, Yamasaki, Hironori, Abiru, Norio, Nakazato, Mio, Kamihira, Shimeru, Maeda, Takahiro

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2007

Language:

english

File:

PDF, 138 KB

english, 2007

41

Exacerbation of autoimmune thyroiditis by a single low dose of whole-body irradiation in non-obese diabetic-H2 h4 mice

Nagayama, Yuji, Kaminoda, Kazuhisa, Mizutori, Yumiko, Saitoh, Ohki, Abiru, Norio

Journal:

International Journal of Radiation Biology

Year:

2008

Language:

english

File:

PDF, 846 KB

english, 2008

42

CD8 + CD122 + T Cells, a Newly Identified Regulatory T Subset, Negatively Regulate Graves’ Hyperthyroidism in a Murine Model

Saitoh, Ohki, Abiru, Norio, Nakahara, Mami, Nagayama, Yuji

Journal:

Year:

2007

Language:

english

File:

PDF, 381 KB

english, 2007

43

Expression of Immunoregulatory Molecules by Thyrocytes Protects Nonobese Diabetic-H2 h4 Mice from Developing Autoimmune Thyroiditis

Nakahara, Mami, Nagayama, Yuji, Saitoh, Ohki, Sogawa, Rintaro, Tone, Shigenobu, Abiru, Norio

Journal:

Year:

2009

Language:

english

File:

PDF, 402 KB

english, 2009

44

Autoantibodies to Insulin, Insulinoma-Associated Antigen-2, and Zinc Transporter 8 Improve the Prediction of Early Insulin Requirement in Adult-Onset Autoimmune Diabetes

Kawasaki, Eiji, Nakamura, Kan, Kuriya, Genpei, Satoh, Tsuyoshi, Kuwahara, Hironaga, Kobayashi, Masakazu, Abiru, Norio, Yamasaki, Hironori, Eguchi, Katsumi

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 115 KB

english, 2010

45

Adoptive Transfer of Antithyrotropin Receptor (TSHR) Autoimmunity from TSHR Knockout Mice to Athymic Nude Mice

Nakahara, Mami, Johnson, Kristian, Eckstein, Anja, Taguchi, Ryo, Yamada, Masanobu, Abiru, Norio, Nagayama, Yuji

Journal:

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

46

Leptin to high-molecular-weight adiponectin ratio is independently correlated with carotid intima-media thickness in men, but not in women

Takamura, Noboru, Hayashida, Naomi, Hagane, Kyoko, Kadota, Koichiro, Yamasaki, Hironori, Abiru, Norio, Ozono, Yoshiyuki, Kamihira, Shimeru, Aoyagi, Kiyoshi, Ishibashi, Kiyomi, Nakazato, Mio, Maeda, Ta

Journal:

Year:

2010

Language:

english

File:

PDF, 760 KB

english, 2010

47

White blood cell count and cardiovascular biomarkers of atherosclerosis

Sekitani, Yui, Hayashida, Naomi, Kadota, Koichiro, Yamasaki, Hironori, Abiru, Norio, Nakazato, Mio, Maeda, Takahiro, Ozono, Yoshiyuki, Takamura, Noboru

Journal:

Year:

2010

Language:

english

File:

PDF, 790 KB

english, 2010

48

T Helper Type 17 Immune Response Plays an Indispensable Role for Development of Iodine-Induced Autoimmune Thyroiditis in Nonobese Diabetic-H2 h4 Mice

Horie, Ichiro, Abiru, Norio, Nagayama, Yuji, Kuriya, Genpei, Saitoh, Ohki, Ichikawa, Tatsuki, Iwakura, Yoichiro, Eguchi, Katsumi

Journal:

Year:

2009

Language:

english

File:

PDF, 309 KB

english, 2009

49

Clinical and Genetic Characteristics of Autoimmune Polyglandular Syndrome Type 3 Variant in the Japanese Population

Horie, Ichiro, Kawasaki, Eiji, Ando, Takao, Kuwahara, Hironaga, Abiru, Norio, Usa, Toshiro, Yamasaki, Hironori, Ejima, Eri, Kawakami, Atsushi

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2012

Language:

english

File:

PDF, 585 KB

english, 2012

50

Induction of Autoimmune Thyroiditis by Depletion of CD4 + CD25 + Regulatory T Cells in Thyroiditis-Resistant IL-17, But Not Interferon-γ Receptor, Knockout Nonobese Diabetic-H2 h4 Mice

Horie, Ichiro, Abiru, Norio, Sakamoto, Hikaru, Iwakura, Yoichiro, Nagayama, Yuji

Journal:

Year:

2011

Language:

english

File:

PDF, 444 KB

english, 2011